That can result in serious side effects such as seizures. Bupropion is an aminoketone antidepressant with a mechanism that is not fully understood.[10] Bupropion seems not to affect monoamine uptake but is known to inhibit the reuptake of norepinephrine and dopamine weakly. The effects on norepinephrine and dopamine appear to lead to its clinical manifestations. Dopamine reuptake inhibition is reportedly very high, while norepinephrine uptake is less potent. Bupropion also acts to a lesser degree on nicotinic and serotonin receptors. In the US – Call your doctor for medical advice about side effects.
Usual Adult Dose for Seasonal Affective Disorder
Postmarketing reports have described seizures in breastfed infants. The relationship of bupropion exposure and these seizures is unclear. Decreased fetal weights were observed at doses of 50 mg/kg/day (approximately 2 times the MRHD on a mg/m² basis) and greater.
Bupropion Side Effects
Before taking bupropion, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Do not take more or less medication or take it more often than prescribed.
What are the forms of Wellbutrin?
Wellbutrin is not prescribed for people younger than 18 years old. No, Wellbutrin (bupropion) is not an SSRI (selective serotonin reuptake inhibitor) or SNRI https://sober-house.org/3-ways-to-pass-a-urine-drug-test/ (serotonin norepinephrine reuptake inhibitor). It is structurally different from other antidepressant drugs, including tricyclic antidepressants and SSRIs.
This is a major reason why patients discontinue their depression medications. But bupropion appears to affect libido less, which can make it a good alternative. (An active ingredient is what makes a drug work.) Wellbutrin is an antidepressant. It belongs to a group of drugs called norepinephrine and dopamine reuptake blockers. Antidepressant medicines may increase the risk of suicidal thoughts or actions in some children, teenagers, or young adults within the first few months of treatment. In a trial in healthy volunteers, efavirenz 600 mg once daily for 2 weeks reduced the AUC and Cmax of bupropion by approximately 55% and 34%, respectively.
- In many people, these symptoms went away after stopping WELLBUTRIN, but in some people symptoms continued after stopping WELLBUTRIN.
- This document does not contain all possible drug interactions.
- This incidence is approximately double that seen in comparable subjects treated with tricyclics or placebo.
- Check with your doctor right away if you have blistering, peeling, or loosening of the skin, red skin lesions, severe acne or a skin rash, sores or ulcers on the skin, or fever or chills with this medicine.
- Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines.
Renal Dose Adjustments
Dosage increase of WELLBUTRIN may be necessary when coadministered with ritonavir, lopinavir, or efavirenz [see CLINICAL PHARMACOLOGY] but should not exceed the maximum recommended dose. Bupropion is primarily metabolized to hydroxybupropion by CYP2B6. The manufacturer directs not to crush, cut, or chew the tablet before taking it.
If you drink alcohol regularly, talk with your doctor before changing the amount you drink. This medicine can also cause seizures in people who drink a lot of alcohol and then suddenly quit drinking methamphetamine withdrawal when they start using the medication. Bupropion is an antidepressant medication used to treat depression and seasonal affective disorder, it also supports smoking cessation and weight management.
Examples of drugs that can cause interactions with bupropion are listed below. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. If you have trouble falling asleep or staying asleep, do not take tablets too close to bedtime.
The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine. The dose of this medicine will be different for different patients. Follow your doctor’s orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.
This medicine can cause you to have a false positive drug screening test. If you provide a urine sample for drug screening, tell the laboratory what is holistic addiction treatment staff that you are taking bupropion. Do not stop using Wellbutrin suddenly, or you could have unpleasant withdrawal symptoms.
Certain antidepressants (MAOIs, SSRIs), antipsychotics (haloperidol, risperidone), and heart medications (beta-blockers, antiarrhythmics) can interact with bupropion. Speak with your pharmacist and doctor to make sure the other medications you take do not interact with bupropion. Some people taking Wellbutrin XL (Wellbutrin or Zyban) have had high blood pressure that is severe, especially when also using a nicotine replacement product (patch or gum). You should not change your dose or stop using Wellbutrin XL suddenly, unless you have a seizure while taking this medicine. Some young people have thoughts about suicide when first taking an antidepressant.